gryllus bimaculatus ethanol extract

Gryllus bimaculatus ethanol extract (GBE) is a natural product derived from the two-spotted cricket, an edible insect used in traditional medicine. It is prepared by extracting dried and ground crickets with 70% ethanol. GBE is rich in proteins and unsaturated fatty acids and has demonstrated a range of pharmacological activities in preclinical models, including anti-thrombotic, anti-inflammatory, antioxidant, and hepatoprotective effects. Its mechanism of action involves the inhibition of platelet glycoprotein IIb/IIIa (integrin αIIb/β3) for anti-platelet activity, modulation of the AKT/mTOR pathway for metabolic effects, and induction of apoptosis in cancer cells. It is primarily studied in academic research for potential applications in cardiovascular disease, liver disease, and metabolic disorders.

Other names

Gryllus bimaculatus extracttwo-spotted cricket ethanol extract