Drug intelligence / Profile preview

GS3-007a

Development stage
Unknown
Lead developer
Changchun GeneScience Pharmaceutical
Modality
Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

GS3-007a is an investigational oral dry suspension formulation of recombinant human growth hormone (rhGH) being developed by Changchun GeneScience Pharmaceutical Co., Ltd. (GenSci) for the treatment of pediatric growth hormone deficiency (PGHD). Unlike traditional rhGH therapies that require daily or weekly subcutaneous injections, GS3-007a is designed for oral administration, which may significantly improve patient compliance and quality of life. The drug acts as an agonist at the growth hormone receptor, mimicking the effects of endogenous growth hormone to stimulate the production of insulin-like growth factor 1 (IGF-1), thereby promoting linear growth and metabolic health in children. It is currently being evaluated in Phase Ib/II clinical trials to assess its safety, pharmacokinetics, and efficacy compared to standard injectable rhGH.

Other names
GS3-007a dry suspensionGS-3-007a dry suspensionGS 3-007a dry suspensionoral recombinant human growth hormone
02

Targets

GHR (Growth hormone receptor)

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