GSK Experimental Dentifrice MFC02753

GSK Experimental Dentifrice MFC02753 is an experimental toothpaste formulation developed by GSK Consumer Healthcare (now Haleon) containing 0.454% w/w stannous fluoride. It is primarily investigated for the treatment and prevention of gingivitis. The formulation utilizes stannous ions (Sn2+) to provide antimicrobial and anti-inflammatory benefits, specifically targeting plaque bacteria and reducing gingival inflammation. In clinical trials, such as the Phase 2 study NCT03848208 conducted in the UK, MFC02753 was evaluated over a 12-week period using the Modified Gingival Index (MGI) and Bleeding Index (BI) to demonstrate its efficacy compared to standard sodium fluoride reference toothpastes.

Other names

experimental 0.454% w/w stannous fluoride toothpasteexperimental stannous fluoride dentifrice