Drug intelligence / Profile preview

GSK2230672

Development stage
Unknown
Lead developer
GSK
Modality
Small Molecules
Administration
Oral
01

Overview

GSK2230672 is an investigational oral small molecule developed by GSK for the treatment of cholestasis. Its mechanism of action involves binding to and inhibiting the deubiquitinating activity of the enzyme Ubiquitin-specific protease 7 (USP7), which may modulate pathways relevant to cholestatic liver diseases. The drug has been evaluated in early-phase clinical trials, including dose-escalation studies in healthy volunteers[1][8].

Other names
gsk-2230672gsk2230672gsk 2230672
02

Targets

USP7

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