Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
GSK2634673F
- Development stage
- Unknown
- Lead developer
- GSK
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Peptides
- Administration
- Intravenous
01
Overview
GSK2634673F is a fluorine-18 ([18F]) labeled synthetic peptide derived from the foot-and-mouth disease virus (FMDV) coat protein. It functions as a highly specific positron emission tomography (PET) radiotracer targeting the integrin alpha(V)beta6. This integrin is typically absent in healthy adult tissues but is significantly upregulated in various cancers and fibrotic conditions, including idiopathic pulmonary fibrosis (IPF). Developed by GSK, the ligand is used to non-invasively quantify alpha(V)beta6 expression levels, providing a potential biomarker for disease activity and treatment response in fibrotic lung diseases. The peptide sequence is based on the A20FMDV2 peptide, which contains the RGD motif recognized by the integrin.
- Other names
- [18F]-FBA-A20FMDV218F-FBA-A20FMDV2alpha(V)beta6 PET ligand
02
Targets
αVβ6 (Integrin αVβ6)
Beyond the preview
Go deeper on GSK2634673F.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on GSK2634673F.