Drug intelligence / Profile preview

GSK2788723

Development stage
Unknown
Lead developer
GSK
Modality
Replacement Enzymes → Therapeutic Enzymes → Recombinant Proteins and Enzymes
Administration
Intravenous
01

Overview

GSK2788723 is an investigational drug developed for the treatment of Hunter syndrome (also known as mucopolysaccharidosis type II, MPS II), a rare lysosomal storage disorder. The drug has been studied in clinical trials to assess potential cross-reactivity with idursulfase, another enzyme replacement therapy used for Hunter syndrome. GSK2788723 is being developed by JCR and GSK[2][7]. Its precise mechanism of action is not detailed in the available sources, but it is likely related to enzyme replacement or modification therapy targeting the underlying enzymatic deficiency characteristic of MPS II.

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