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GSK2788723 is an investigational drug developed for the treatment of Hunter syndrome (also known as mucopolysaccharidosis type II, MPS II), a rare lysosomal storage disorder. The drug has been studied in clinical trials to assess potential cross-reactivity with idursulfase, another enzyme replacement therapy used for Hunter syndrome. GSK2788723 is being developed by JCR and GSK[2][7]. Its precise mechanism of action is not detailed in the available sources, but it is likely related to enzyme replacement or modification therapy targeting the underlying enzymatic deficiency characteristic of MPS II.
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