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GSK2838502A
- Development stage
- Unknown
- Lead developer
- GSK
- Modality
- Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
GSK2838502A is an investigational protein subunit vaccine developed by GSK Biologicals for the prevention of infections caused by Non-typeable Haemophilus influenzae (NTHi). It was developed as part of a program to reduce the frequency of exacerbations in patients with chronic obstructive pulmonary disease (COPD). The vaccine was evaluated in Phase 1 clinical trials (such as NCT02075541) to assess safety, reactogenicity, and immunogenicity in current and former smokers aged 50 to 70. GSK2838502A represents one of several formulations tested, which typically utilize recombinant NTHi surface proteins (such as Protein D, Protein E, and Pilin A) and may be combined with the AS01 adjuvant system to enhance the immune response.
- Other names
- NTHi vaccineNon-typeable Haemophilus influenzae vaccineNTHi-10-AS01ENTHi10-AS01ENTHi 10-AS01E
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