GSK2881078

**GSK2881078** is an orally bioavailable, nonsteroidal, small molecule selective androgen receptor modulator (SARM) developed by GSK. It is designed to induce anabolic effects on muscle with reduced androgenic side effects compared to traditional anabolic steroids. The drug has been investigated primarily for the treatment of muscle weakness and functional limitations associated with chronic and acute illnesses, including age-related muscle atrophy (sarcopenia) and cachexia in elderly adults. Clinical studies have shown that GSK2881078 produces dose-dependent increases in lean body mass, with evidence of enhanced sensitivity in women. The compound has generally been well tolerated in clinical trials[3][4][6][7].

Other names

(R)-1-(1-(methylsulfonyl)propan-2-yl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile1-[(2R)-1-methylsulfonylpropan-2-yl]-4-(trifluoromethyl)indole-5-carbonitrile