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**GSK4001785A** is an investigational vaccine candidate developed by GSK targeting *Shigella* infection. It is part of the altSonflex1-2-3 GMMA (Generalized Modules for Membrane Antigens) vaccine platform, designed to elicit bactericidal antibodies effective against a panel of drug-resistant *Shigella* clinical isolates. The vaccine aims to provide protection against shigellosis, a major cause of diarrheal disease, particularly in vulnerable populations in low- and middle-income countries, through intramuscular administration in early-phase clinical trials.
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