Drug intelligence / Profile preview

GSK513026

Development stage
Unknown
Lead developer
GSK
Modality
Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
Administration
Intramuscular
01

Overview

GSK513026 is an 11-valent pneumococcal conjugate vaccine developed by GSK for the prevention of invasive pneumococcal disease and pneumonia caused by Streptococcus pneumoniae. As a conjugate vaccine, it consists of pneumococcal polysaccharides from 11 different serotypes conjugated to carrier proteins to enhance the immune response, particularly in populations with reduced immune fitness such as the elderly. The vaccine was evaluated in Phase 2 clinical trials to assess its safety, reactogenicity, and immunogenicity in healthy adults aged 65 years and older, comparing various formulations with and without adjuvants against the licensed 23-valent polysaccharide vaccine (Pneumovax 23).

Other names
11-valent pneumococcal conjugate vaccine11-valent pneumococcal protein vaccine
02

Targets

BCR (Immunoglobulin G B Cell Receptor)TCR (T cell antigen receptor complex)

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