Drug intelligence / Profile preview

guaifenesin + doxylamine succinate + etafedrine hydrochloride

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

This is a **combination drug** containing three active ingredients commonly used to treat symptoms associated with cough, upper respiratory congestion, and bronchospasm: - **Guaifenesin** is an expectorant that helps thin and loosen mucus in the airways, making it easier to clear from the respiratory tract. - **Doxylamine succinate** is a first-generation antihistamine with anticholinergic and sedative properties, often used to reduce symptoms such as runny nose and sneezing associated with upper respiratory tract infections. - **Etafedrine hydrochloride** is a sympathomimetic agent and selective beta-2 adrenoceptor agonist, structurally related to ephedrine, which acts as a bronchodilator and has decongestant activity, thereby relieving bronchospasm and nasal congestion. This combination is not widely marketed under a single well-known brand name and appears in the medical literature for treatment of respiratory conditions such as chronic bronchitis, and bronchospasm, and may also be used for cough and cold symptoms. It is formulated as an **oral pharmaceutical** and is typically used for symptomatic respiratory relief in conditions involving cough, mucus hypersecretion, or bronchospasm[1][7].

Other names
guaifenesin + doxylamine succinate + etafedrine hydrochloride
02

Targets

ADRB2 (β2)HRH1 (Histamine H1 Receptor)

Beyond the preview

Go deeper on guaifenesin + doxylamine succinate + etafedrine hydrochloride.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on guaifenesin + doxylamine succinate + etafedrine hydrochloride.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call