guaifenesin + pseudoephedrine + hydrocodone

guaifenesin + pseudoephedrine + hydrocodone is a fixed-dose combination pharmaceutical product used for the symptomatic relief of cough, nasal congestion, and chest congestion associated with the common cold or influenza. It combines three active ingredients with distinct mechanisms: **guaifenesin**, an expectorant that increases the volume and reduces the viscosity of respiratory tract secretions; **pseudoephedrine**, a sympathomimetic decongestant that stimulates alpha-adrenergic receptors to produce vasoconstriction in the nasal mucosa; and **hydrocodone**, an opioid antitussive that suppresses the cough reflex by acting directly on the cough center in the medulla. Developed by entities such as Shenzhen Pharmaceutical Factory, this combination is typically administered as an oral solution and is indicated for adult patients requiring multi-symptom relief from upper respiratory tract infections.

Brand names

Hycofenix

Other names

hydrocodone bitartrate, pseudoephedrine hydrochloride, and guaifenesin oral solution