Guangxi Normal Univ. PLK1 compound 4Bb

Guangxi Normal Univ. PLK1 compound 4Bb: sourced facts only. name: "Compound 4Bb was identified as a new potent PLK1 inhibitor with a KD value of 0.29 μM." [PMID:38657480]; target: "Compound 4Bb was identified as a new potent PLK1 inhibitor with a KD value of 0.29 μM." [PMID:38657480]; developer: "State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources/Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, China." [PMID:38657480]; stage: "Subcutaneous and oral administration of 4Bb could effectively inhibit the growth of drug-resistant tumors in vivo, doubling the survival time of tumor bearing mice without side effects in normal tissues." [PMID:38657480]