Guangzhou Medical Univ. DDX10 compound 5o

Guangzhou Medical Univ. DDX10 compound 5o: sourced facts only. name: "Notably, compound 5o was identified as the first inhibitor of DEAD-box helicase 10 (DDX10)." [PMID:40063343]; target: "Notably, compound 5o was identified as the first inhibitor of DEAD-box helicase 10 (DDX10)." [PMID:40063343]; developer: "Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, The State & NMPA Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, PR China." [PMID:40063343]; stage: "An in vivo xenograft assay further confirmed the therapeutic potential of compound 5o, demonstrating tumor growth inhibition rates of 60%, 78%, and 88% at doses of 5 mg/kg, 10 mg/kg, and 20 mg/kg, respectively." [PMID:40063343]