Drug intelligence / Profile preview

Guangzhou Univ. of Chinese Medicine STAT3 compound c8

Development stage
Unknown
Lead developer
Guangzhou University of Chinese Medicine
01

Overview

Guangzhou Univ. of Chinese Medicine STAT3 compound c8: sourced facts only. name: "The cellular thermal shift assay (CETSA) demonstrated that c8 stabilized STAT3 protein, suggesting a potential interaction." [PMID:42759393]; target: "The cellular thermal shift assay (CETSA) demonstrated that c8 stabilized STAT3 protein, suggesting a potential interaction." [PMID:42759393]; developer: "State Key Laboratory of Traditional Chinese Medicine Syndrome/School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, People's Republic of China." [PMID:42759393]; stage: "In vivo, c8 at a dose of 25-50 mg/kg showed significant antitumor efficacy in A549 xenografts." [PMID:42759393]

02

Targets

STAT3 (Signal Transducer and Activator of Transcription 3)

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