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Guanshitong Hanhua pill is a Traditional Chinese Medicine (TCM) hospital preparation developed by the Henan Province Hospital of TCM for the treatment of advanced esophageal cancer. It is specifically utilized in patients who are ineligible for or have progressed after standard chemotherapy. The formulation is designed as a pill intended for buccal dissolution (hanhua), which allows the active herbal components to act locally on the esophageal mucosa and tumor site as the medication melts in the mouth. In clinical research, such as the trial ChiCTR2000034844, it is evaluated as part of a multi-component TCM regimen to improve clinical benefit rates, quality of life (KPS performance), and immune function, while addressing symptoms of esophageal obstruction.
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