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Guanxin Danshen Dripping Pills
- Development stage
- Unknown
- Lead developer
- Buchang Pharmaceutical Group
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral, Sublingual
01
Overview
Guanxin Danshen Dripping Pills is a Traditional Chinese Medicine (TCM) product widely used in China for the treatment of cardiovascular diseases, particularly coronary artery disease (CAD) and angina pectoris. The formulation typically includes extracts from *Salvia miltiorrhiza* (Danshen), *Panax notoginseng* (Sanqi), and *Dalbergia odorifera* (Jiangxiang). It is designed to promote blood circulation, resolve blood stasis, and regulate qi to alleviate pain. The dripping pill dosage form is a modern TCM preparation that enhances bioavailability and allows for rapid absorption, often used for both chronic management and acute relief of chest pain. Clinical studies have expanded its investigation into the treatment of CAD patients with comorbid psychological distress, such as depression and anxiety, exploring its potential systemic anti-inflammatory and neuroprotective effects.
- Brand names
- Guanxin Danshen Dripping Pills
- Other names
- Guanxin Danshen Diwan
02
Targets
NOS3 (eNOS)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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