Drug intelligence / Profile preview

Guanxin V

Development stage
Preclinical
Modality
Implantable Devices → Device-based Delivery → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
Administration
Oral
01

Overview

Guanxin V is a traditional Chinese medicine (TCM) formula used primarily for the treatment of acute myocardial infarction and related cardiovascular conditions. It exerts cardioprotective effects by alleviating apoptosis, oxidative stress damage, and fibrosis in cardiac tissue. Mechanistically, its action is associated with down-regulation of the TGF-β1 signaling pathway, which plays a key role in cardiac remodeling after injury. Preclinical studies have demonstrated that Guanxin V can reduce cell death and fibrosis while improving mitochondrial function in models of heart attack[1]. The specific herbal composition of Guanxin V is not detailed in the available sources, but it is recognized as a multi-component TCM product.

Brand names
Guanxin V
Other names
Guanxin V

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