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Guanxinkang Granules

Development stage: Unknown
Lead developer: Longhua Hospital Shanghai University of Traditional Chinese Medicine
Administration: Oral

Overview

Guanxinkang Granules is a Traditional Chinese Medicine (TCM) compound formulation developed by Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine. It is specifically designed for the treatment of coronary heart disease (CHD) and carotid atherosclerosis. The formulation is based on the TCM therapeutic principles of invigorating Qi, promoting blood circulation, and resolving phlegm. Clinical evaluation of Guanxinkang Granules focuses on its potential to reduce carotid plaque burden, alleviate angina symptoms, and improve quality of life and sleep in patients with atherosclerotic cardiovascular disease. Mechanistically, the granules are studied for their ability to modulate lipid profiles and immune-inflammatory markers associated with the progression of atherosclerotic plaques.

Brand names: Guanxinkang Granules
Other names: Guanxinkang KeliGuan-Xin-Kang Granules

Targets

IL1B (Interleukin-1 beta)MMP9 (Matrix metalloproteinase-9)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)ESR1 (ERα)TP53 (Cellular Tumor Antigen p53 R175H)IL-6 (Interleukin 6)

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