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Guben Huayu Formula is a traditional Chinese herbal medicine (CHM) prescription used primarily for the treatment of psoriasis vulgaris (PV), an inflammatory and chronically relapsing dermatological disease. The formula is composed of multiple herbal ingredients based on principles of traditional Chinese medicine aimed at "tonifying the kidney" and "removing blood stasis." It has been studied in clinical settings both as a monotherapy and in combination with other treatments such as biologics (e.g., ixekizumab) or stem cell therapies. Mechanistically, while the precise molecular targets are not fully elucidated due to its multi-component nature, it is believed to exert immunomodulatory effects that help reduce inflammation and relapse rates in PV patients[1][3][6]. Clinical trials have evaluated its efficacy and safety for moderate to severe psoriasis[6][8].
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