guben quyu jiedu fang

Guben Quyu Jiedu Fang (固本祛瘀解毒方) is a traditional Chinese medicine (TCM) formula used as a multi-herbal compound. Its name translates to "Strengthen the Root, Remove Stasis, and Detoxify Formula." The formula is designed according to TCM principles to tonify vital energy (qi), remove blood stasis, and clear toxins from the body. It is typically used in the context of chronic diseases characterized by deficiency of vital energy with concurrent blood stasis and toxin accumulation. Mechanistically, Guben Quyu Jiedu Fang acts through immunomodulation—enhancing cellular immunity while suppressing overactive humoral immunity—thus achieving a bidirectional regulatory effect on immune function[1]. This makes it particularly relevant for conditions where immune dysfunction plays a role, such as certain cancers or chronic inflammatory diseases. Clinical studies have explored its use in combination with chemotherapy for advanced non-small cell lung cancer[2] and for chronic obstructive pulmonary disease complicated by obstructive sleep apnea hypopnea syndrome[3]. The specific herbal composition may vary but generally includes herbs that tonify qi (such as Astragalus membranaceus/Huangqi), promote blood circulation and resolve stasis (such as Salvia miltiorrhiza/Danshen), and clear heat/toxins. The formula is not standardized across all sources; it may be tailored based on individual patient presentation according to TCM diagnostic patterns.

Brand names

Gubenquyujiedu

Other names

固本祛瘀解毒方