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Gubenquyujiedu is a Traditional Chinese Medicine (TCM) herbal formula developed by the Xiyuan Hospital of the China Academy of Chinese Medical Sciences. It is primarily investigated for the treatment of chronic obstructive pulmonary disease (COPD), targeting both the acute exacerbation and remission phases. The formula is designed to improve activity endurance and clinical symptoms in COPD patients. Research suggests its mechanism may involve the modulation of inflammatory factors and specific microRNAs, such as miRNA-1 and miRNA-199a-5p, which are associated with muscle function and inflammatory responses in pulmonary diseases.
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