Drug intelligence / Profile preview

Guduchi Ghan Vati

Development stage
Unknown
Lead developer
Ministry of Ayush
Modality
Drug Delivery Systems
Administration
Oral
01

Overview

Guduchi Ghan Vati (also known as Giloy Ghan Vati or Samshamani Vati) is an Ayurvedic formulation prepared from the concentrated aqueous extract of Guduchi (Tinospora cordifolia) stem. It's primarily used as an immunomodulator and for various health conditions including fever, respiratory issues, and diabetes management. ## Composition and Preparation Guduchi Ghan Vati is prepared from the dry concentrated aqueous extract of the stem of Guduchi (Tinospora cordifolia). Each tablet typically contains 250 mg of this extract[1][3]. The formulation is standardized to contain not less than 2.5% bitters with an herb extract ratio of 10:1[3]. ## Therapeutic Uses This Ayurvedic medication has multiple therapeutic applications: 1. **Immune System Support**: Guduchi Ghan Vati is widely recognized as an immunomodulator that enhances immunity and helps protect against various infections[1][3][4]. 2. **Respiratory Health**: It helps manage respiratory conditions including cough, asthma, and COPD, maintaining a healthy respiratory tract[4]. 3. **Fever Management**: Traditionally used for chronic and recurrent fevers due to its antipyretic properties[4][5]. 4. **Diabetes Management**: It helps improve insulin production and control high blood sugar levels due to its bitter properties that balance Kapha-Pitta doshas in Ayurvedic terms[4]. 5. **COVID-19 Prevention**: Recent studies have investigated its potential in preventing COVID-19 infection and reducing the severity of symptoms[1][3][5]. 6. **Joint and Musculoskeletal Health**: It may promote healthy bones, joints, muscles, ligaments, and interstitial tissues, supporting overall structural integrity and potentially helping with rheumatism[7]. 7. **Other Benefits**: It's also used for conditions such as muscular weakness, allergies, elevated uric acid levels, jaundice, anemia, and skin/hair/nail health[7]. ## Dosage and Administration The typical dosage of Guduchi Ghan Vati is: - 1-2 tablets (250-500 mg each) twice daily after meals with water[1][2][3] - For COVID-19 prevention studies, the dosage used was 1g daily (500 mg twice daily) for 28-45 days[1][3][5] ## Safety Profile Guduchi Ghan Vati is generally considered safe when taken as prescribed. Clinical studies have reported no major adverse drug reactions[3]. However, some precautions should be noted: - Excess consumption for extended periods may cause heating sensations in the body and stomach troubles[2] - People taking antidiabetic medications should consult a physician before use as it may lower blood glucose levels[2][4] - Pregnant and lactating women should seek medical advice before use[2] ## Scientific Evidence Several clinical studies have investigated Guduchi Ghan Vati's efficacy: 1. A multicenter, controlled study showed improved perceived immune status in individuals at risk of SARS-CoV-2 infection[1] 2. Another study found that while the difference in COVID-19 incidence between Guduchi Ghan Vati users and control groups was statistically non-significant, the severity of COVID-19 was significantly lower in the Guduchi group[3] 3. The number of episodes and severity of non-COVID-19 illness were also significantly lower in participants taking Guduchi Ghan Vati compared to control groups[3] Guduchi Ghan Vati represents a traditional Ayurvedic approach to health maintenance and disease prevention, with growing scientific interest in its immunomodulatory and therapeutic properties.

Brand names
Giloy GhanvatiPatanjali Giloy Ghan VatiBaidyanath Guduchi Ghan VatiHimalaya Guduchi
Other names
Giloy Ghan VatiSamshamani Vati
02

Targets

TLR6

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