Drug intelligence / Profile preview

Gui-Fu-Di-Huang Pill

Development stage: Unknown
Lead developer: Beijing Anding Hospital
Administration: Oral

Overview

Gui-Fu-Di-Huang Pill is a classic Traditional Chinese Medicine (TCM) formula composed of eight herbal ingredients, primarily used to warm and tonify Kidney Yang. It is a modification of the Liu Wei Di Huang Wan (Six-Ingredient Rehmannia Pill) formula, with the addition of *Cinnamomum cassia* (Rou Gui) and *Aconitum carmichaelii* (Zhi Fu Zi). In modern clinical research, it is being investigated as an adjunctive therapy to selective serotonin reuptake inhibitors (SSRIs) like escitalopram for the treatment of depressive disorder, specifically targeting hypodynamic symptoms such as fatigue and lack of energy in patients with a "Yang-deficiency" constitution. The formula is hypothesized to restore metabolic and endocrine balance by modulating the hypothalamic-pituitary-adrenal (HPA) axis and warming the "Gate of Vitality" (Ming Men) in TCM terms.

Brand names: Guifu Dihuang Wan
Other names: Gui-Fu-Di-Huang PillKidney Qi PillJin Kui Shen Qi WanCinnamon and Aconite Pill with Rehmannia

Targets

EGFR (Epidermal growth factor receptor)

Beyond the preview

Go deeper on Gui-Fu-Di-Huang Pill.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Gui-Fu-Di-Huang Pill.

Explore the full profile