Drug intelligence / Profile preview

Guilin Medical Univ. CA IX compound 7m

Development stage
Preclinical
Lead developer
Guilin Medical University
01

Overview

Guilin Medical Univ. CA IX compound 7m: sourced facts only. name: "Additionally, 7m exhibits potent inhibitory activity against CA IX (IC50 = 80.45 ± 39.7 nM) and shows enhanced antitumor activity under hypoxic conditions compared to normoxic conditions." [PMID:40515697]; target: "Additionally, 7m exhibits potent inhibitory activity against CA IX (IC50 = 80.45 ± 39.7 nM) and shows enhanced antitumor activity under hypoxic conditions compared to normoxic conditions." [PMID:40515697]; developer: "Guangxi Key Laboratory of Drug Discovery and Optimization, School of Pharmacy, Guilin Medical University, Guilin 541004, China." [PMID:40515697]; stage: "The representative compound 7m demonstrated significant antitumor effects against the MDA-MB-231 cell line both in vitro and in vivo." [PMID:40515697]

02

Targets

CA9 (Carbonic anhydrase IX)

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