Drug intelligence / Profile preview

guizhi longmu tang + shudi pingchan fang

Development stage
Unknown
Lead developer
Longhua Hospital Shanghai University of Traditional Chinese Medicine
Administration
Oral
01

Overview

Guizhi Longmu Tang + Shudi Pingchan Fang is a combination Traditional Chinese Medicine (TCM) herbal decoction primarily investigated for the treatment of Parkinson's disease (PD). Guizhi Longmu Tang is a classical formula traditionally used to harmonize Yin and Yang and calm the spirit, while Shudi Pingchan Fang (Prepared Rehmannia Tremor-Calming Formula) is an empirical formula designed to nourish the Liver and Kidney and extinguish internal wind to alleviate tremors. The combination is used to address both the motor symptoms (such as tremors and rigidity) and non-motor symptoms (such as anxiety and sleep disorders) associated with Parkinson's disease. Clinical research, particularly in China, suggests that the formula may exert neuroprotective effects by modulating the dopaminergic system, reducing oxidative stress in the substantia nigra, and regulating neuroinflammatory cytokines.

Other names
Guizhi Longmu Tang + Shudi Pingchan Fang桂枝龙牡汤 + 熟地平颤方GZLM + SDPF
02

Targets

DRD (Dopamine receptors)

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