Drug intelligence / Profile preview

Guizhou Medical Univ. acetylcholinesterase compound 11e

Development stage
Preclinical
Lead developer
Guizhou Medical University
01

Overview

Guizhou Medical Univ. acetylcholinesterase compound 11e: sourced facts only. name: "Among them, compound 11e exhibited the most potent inhibition of electric eel and human acetylcholinesterase enzymes with IC50 values of 6.72 ± 0.09 and 8.91 ± 0.08 μM, respectively." [PMID:37186997]; target: "Among them, compound 11e exhibited the most potent inhibition of electric eel and human acetylcholinesterase enzymes with IC50 values of 6.72 ± 0.09 and 8.91 ± 0.08 μM, respectively." [PMID:37186997]; developer: "State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550004, Guizhou, China; School of Pharmacy, Guizhou Medical University, Guiyang 550004, China; National Engineering Research Center of Miao's Medicines & Engineering Research Center for the Development and Application of Ethnic Medicine and TCM, Ministry of Education, Guiyang 550004, Guizhou, China." [PMID:37186997]; stage: "In addition, in vivo studies revealed that compound 11e significantly attenuated learning and memory impairment in an AD mice model." [PMID:37186997]

02

Targets

Acetylcholinesterase

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