Guizhou Medical Univ. PTP1B compound 5l

Guizhou Medical Univ. PTP1B compound 5l: sourced facts only. name: "The compound 5l that possessed the best inhibition activity on both α-glucosidase and α-amylase (IC50 = 9.79 ± 0.21, 6.36 ± 0.16 μM, respectively) also exhibited a fine inhibitory effect on PTP1B with an IC50 value of 19.08 ± 4.52 μM, as the reference drug ursolic acid of 4.43 ± 0.40 μM." [PMID:41604801]; target: "The compound 5l that possessed the best inhibition activity on both α-glucosidase and α-amylase (IC50 = 9.79 ± 0.21, 6.36 ± 0.16 μM, respectively) also exhibited a fine inhibitory effect on PTP1B with an IC50 value of 19.08 ± 4.52 μM, as the reference drug ursolic acid of 4.43 ± 0.40 μM." [PMID:41604801]; developer: "State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Provincial Engineering Research Center for the Development and Application of Ethnic Medicine and TCM, Guizhou Medical University, Guian New Area, 561113, China." [PMID:41604801]