Guizhou Medical Univ. PTP1B compound 8a

Guizhou Medical Univ. PTP1B compound 8a: sourced facts only. name: "Therefore, 8a was chosen to detect the inhibitory activities on PTP1B and α-amylase, the results revealed that 8a had the potential to be PTP1B (IC50 = 47.0 ± 0.5 μM) and α-amylase (IC50 = 30.62 ± 2.13 μM) inhibitor." [PMID:39378828]; target: "Therefore, 8a was chosen to detect the inhibitory activities on PTP1B and α-amylase, the results revealed that 8a had the potential to be PTP1B (IC50 = 47.0 ± 0.5 μM) and α-amylase (IC50 = 30.62 ± 2.13 μM) inhibitor." [PMID:39378828]; developer: "Clinical Trails Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, China; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang, China." [PMID:39378828]; stage: "Importantly, the in vivo sucrose-loading test displayed 8a had potential to reduce the postprandial blood glucose." [PMID:39378828]