Drug intelligence / Profile preview

Guizhou Medical Univ. ROR1 compound 7h

Development stage
Preclinical
Lead developer
Guizhou Medical University
01

Overview

Guizhou Medical Univ. ROR1 compound 7h: sourced facts only. name: "Collectively, our work suggested that the ROR1 inhibitor 7h might be a novel drug candidate for NSCLC treatment." [PMID:39591876]; target: "Collectively, our work suggested that the ROR1 inhibitor 7h might be a novel drug candidate for NSCLC treatment." [PMID:39591876]; developer: "State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China; Natural Products Research Center of Guizhou Province, Guiyang 550014, China." [PMID:39591876]; stage: "MTT assay showed that compound 7h exhibited the best anti-cancer properties with IC50 values of 18.16, 8.11 and 3.5 μM against A549, PC9 and H1975 cells, respectively." [PMID:39591876]

02

Targets

ROR1 (Receptor tyrosine kinase-like orphan receptor 1)

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