Guizhou Univ. HDAC6 compound 6d

Guizhou Univ. HDAC6 compound 6d: sourced facts only. name: "Among them, compound 6d exhibited potent inhibitory activity, displaying nanomolar inhibition of HDAC6 (IC₅₀ = 0.074 μM) with a high selectivity index of 52.4 over HDAC1, which significantly exceeds the positive control SAHA." [PMID:42409124]; target: "Among them, compound 6d exhibited potent inhibitory activity, displaying nanomolar inhibition of HDAC6 (IC₅₀ = 0.074 μM) with a high selectivity index of 52.4 over HDAC1, which significantly exceeds the positive control SAHA." [PMID:42409124]; developer: "School of Pharmaceutical Sciences, Guizhou University, Guiyang 550025, China." [PMID:42409124]; stage: "Moreover, 6d effectively inhibited the proliferation of U87-MG glioma cells (IC₅₀ = 2.65 μM) and triggered dose-dependent apoptosis and G2/M phase cell cycle arrest, with superior efficacy compared to SAHA." [PMID:42409124]