Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Gushukang
- Development stage
- Phase 4
- Lead developer
- Beijing Konruns Pharmaceutical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Gushukang is a traditional Chinese herbal compound medicine approved and widely used in China for the prevention and treatment of osteoporosis. It is formulated from multiple herbs, including Herba Epimedii, Rehmannia glutinosa, and Rhizoma Drynariae. The drug acts by promoting osteoblast differentiation (bone formation) and inhibiting osteoclast differentiation (bone resorption), thereby increasing bone mineral density. Mechanistic studies suggest that its effects are mediated through modulation of calcium homeostasis and activation of the BMP-2/Smads signaling pathway. Additionally, it has been shown to induce type-H vessel formation in bone tissue via upregulation of hypoxia inducible factor-1 alpha (HIF-1α), contributing to improved bone vascularization and health[5][6][1]. Clinical studies have demonstrated efficacy in both primary osteoporosis and postmenopausal osteoporosis[2][3].
- Brand names
- GushukangGushukang Jiaonang
- Other names
- GuShuKangGSK
02
Targets
CaSR (Extracellular calcium-sensing receptor)HIF1A (Hypoxia-inducible factor 1-alpha)NFE2L2 (Nuclear factor (erythroid-derived 2)-like 2)
Beyond the preview
Go deeper on Gushukang.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Gushukang.