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Gushuling (GSL) is a traditional Chinese medicine (TCM) hospital preparation that has been widely used in clinical practice, particularly for the treatment of osteoporosis. It is composed of multiple herbal ingredients, though the exact formulation may vary by institution. The mechanism of action is believed to involve modulation of bone metabolism and improvement in bone density, but specific molecular targets or pathways have not been fully elucidated. Its use is primarily based on TCM principles and empirical evidence from clinical practice in China[9].
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