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Gusongbao
- Development stage
- Unknown
- Lead developer
- Guizhou Sanli Pharmaceutical
- Administration
- Oral
01
Overview
Gusongbao is a Traditional Chinese Medicine (TCM) formulation primarily used for the treatment of bone-related disorders, including osteoporosis and skeletal fluorosis. It is composed of several herbal extracts, typically including *Epimedium brevicornu*, *Psoralea corylifolia*, *Rehmannia glutinosa*, and *Anemarrhena asphodeloides*. The formulation is designed to modulate bone metabolism by promoting osteoblast proliferation and activity while inhibiting osteoclast-mediated bone resorption. In clinical research, particularly in the Guizhou province of China, Gusongbao has been evaluated for its efficacy in treating endemic skeletal fluorosis, a condition caused by chronic fluoride exposure that leads to significant skeletal deformities and joint pain. It is often administered as part of a multi-regimen approach to improve bone mineral density and functional outcomes in patients with metabolic bone diseases.
- Brand names
- Gusongbao骨松宝
- Other names
- Gusongbao CapsuleGusongbao Granules
02
Targets
Receptor activator of nuclear factor kappa-B ligand–Receptor activator of nuclear factor kappa-B–Osteoprotegerin signaling axisESR1 (ERα)
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