Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Guwei Capsule
- Development stage
- Unknown
- Lead developer
- Buchang Pharmaceuticals
- Administration
- Oral
01
Overview
Guwei Capsule (骨痿胶囊) is a Traditional Chinese Medicine (TCM) formulation developed and manufactured by Shaanxi Buchang Pharmaceutical for the treatment of osteoporosis and related bone atrophy disorders (Guwei syndrome). The drug is composed of several herbal extracts, including *Epimedium brevicornu*, *Rehmannia glutinosa*, *Drynaria fortunei*, and *Psoralea corylifolia*. According to TCM theory, it is designed to 'tonify the kidney and strengthen the bone.' Mechanistically, it acts as a bone metabolism regulator by modulating the RANKL/OPG signaling pathway to inhibit osteoclast activity and promoting osteoblast differentiation through the upregulation of Bone Morphogenetic Protein 2 (BMP-2). Additionally, the presence of phytoestrogens in its herbal components allows for the modulation of estrogen receptor signaling, making it particularly effective for postmenopausal and senile osteoporosis.
- Brand names
- Guwei Capsule骨痿胶囊
- Other names
- Guwei Jiaonang
02
Targets
ESR1 (ERα)BMP2 (Bone morphogenetic protein 2)RANKL (Receptor Activator for Nuclear Factor-kappa B Ligand)
Beyond the preview
Go deeper on Guwei Capsule.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Guwei Capsule.