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GW-TT3 is a small molecule new chemical entity (NCE) being developed by Gateway Biotechnology for the treatment of tinnitus. It is currently in the preclinical stage of development, with animal pharmacodynamic and pharmacokinetic studies underway to evaluate its efficacy and safety profile. Gateway Biotechnology, a company focused on hearing disorders, targets several cellular pathways including T-type calcium channels, inflammatory response pathways, and reactive oxygen/nitrogen species (ROS/RNS); however, the specific biological target and mechanism of action for GW-TT3 have not been publicly disclosed.
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