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Gynoclear
- Development stage
- Unknown
- Lead developer
- Metagenics
- Administration
- Oral
01
Overview
Gynoclear is a modified traditional Chinese herbal medicine (TCM) formulation developed by Metagenics (Aust) Pty Ltd for the management of endometriosis-related pain. Based on the classical Gui Zhi Fu Ling Wan (GZFLW) formula, Gynoclear is a multi-herb botanical product delivered in capsule form. It contains six active herbal ingredients: *Carthamus tinctorius* (Safflower), *Cinnamomum cassia* (Chinese cinnamon), *Poria cocos* (Hoelen), *Paeonia suffriticosa* (Tree peony), *Paeonia lactiflora* (Peony), and *Salvia miltiorrhiza* (Red sage). The formulation differs from the traditional GZFLW by the addition of *Salvia miltiorrhiza* (Dan Shen) and the substitution of *Semen persicae* (Tao Ren) with *Carthamus tinctorius* (Hong Hua). Gynoclear is currently being evaluated in clinical trials for its efficacy in reducing non-cyclical pelvic pain, dysmenorrhoea, and dyspareunia in women with endometriosis. Its therapeutic effects are attributed to broad anti-inflammatory activity and potential modulation of estrogen receptor pathways.
- Brand names
- Gynoclear
- Other names
- modified Gui Zhi Fu Ling Wan
02
Targets
ER (Estrogen receptor)
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