Drug intelligence / Profile preview

GYNORYLAQ

Development stage
Phase 1
Lead developer
Biogenea
Modality
Peptides, Vaccines & Immunotherapeutics
Administration
Intramuscular, Subcutaneous
01

Overview

GYNORYLAQ (specifically GYNORYLAQ-TM) is a personalized neoantigenic peptide vaccine developed by Biogenea Pharmaceuticals for the treatment of high-risk or recurrent endometrial carcinoma. The vaccine is designed using the GYNORYLAQ-EC™ quantum-classical engine, which identifies patient-specific neoantigens to elicit a targeted T-cell immune response. It is currently being evaluated in Phase I clinical trials (e.g., the GYNORYLAQ-VLINIVAL study) in combination with standard-of-care regimens. The vaccine is manufactured to GMP standards and is tailored to the unique genetic profile of each patient's tumor.

Brand names
GYNORYLAQ
Other names
GYNORYLAQ-VLINIVAL
02

Targets

MHC I (MHC class I})MHC II (Major histocompatibility complex class II receptor)TCR (T cell antigen receptor complex)

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