Drug intelligence / Profile preview

Gynura pseudochina var. hispida

Development stage
Unknown
Administration
Topical, Oral
01

Overview

Gynura pseudochina var. hispida is a medicinal plant from the Asteraceae family traditionally used in Thailand for treating chronic and acute inflammation. It contains bioactive compounds that inhibit the NF-κB pathway and suppress pro-inflammatory cytokines. The plant has demonstrated clinical efficacy in treating mild to moderate psoriasis with minimal side effects, comparable to 0.1% triamcinolone cream. However, caution is advised due to potential presence of hepatotoxic pyrrolizidine alkaloids.

Other names
Gynura pseudochina DC. var. hispida Thv.Gynura pseudochina (L.) var. hispida Thv.
02

Targets

NF-κBIL1B (Interleukin-1 beta)IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))

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