Drug intelligence / Profile preview

H-1129

Development stage
Preclinical
Lead developer
D. Western Therapeutics Institute
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

H-1129 is a small molecule drug candidate developed by D. Western Therapeutics Institute (DWTI) for the treatment of keratoconjunctival diseases associated with immune disorders. The compound is currently in the preclinical stage, with the company preparing for clinical trial applications (Pre-IND) in Japan. While the specific molecular target and mechanism of action have not been publicly disclosed, the drug is being developed internally by DWTI, a company that specializes in the discovery of protein kinase inhibitors for ophthalmic and other conditions using its proprietary drug discovery platforms.

02

Targets

HSP90AA1 (Heat shock protein HSP90-alpha)ROCK1 (Rho-associated coiled-coil containing protein kinase 1)

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