Drug intelligence / Profile preview

H-biota AB-21

Development stage
Unknown
Lead developer
AB-BIOTICS
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

H-biota AB-21 is an oral probiotic dietary supplement developed by AB-Biotics (in partnership with Kaneka and Almus Pharma) to support respiratory and immune health. The formulation consists of a patented blend of four probiotic strains—Lactiplantibacillus plantarum KABP022, KABP023, and KABP033, along with Pediococcus acidilactici KABP021—combined with Vitamin D3 (cholecalciferol). H-biota AB-21 acts via the gut-lung axis to modulate the host's immune response, enhance gut barrier function, and reduce systemic inflammation. Clinical studies have demonstrated its efficacy in accelerating recovery, reducing viral load, and shortening the duration of fever and discomfort in outpatients with mild-to-moderate COVID-19 and children with viral upper respiratory tract infections.

Brand names
H-biota AB-21
Other names
AB-21AB21AB 21H-biota ab-21Ейч-биота аб-21
02

Targets

VDR (Vitamin D receptor)

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