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The H1N1 influenza vaccine is a monovalent or trivalent inactivated or recombinant vaccine designed to protect against the Influenza A (H1N1) virus, which is also known as "swine flu." It works by stimulating the immune system to produce antibodies against the H1N1 viral antigens, thereby providing immunity and reducing the risk of infection. The specific strains included in the vaccine are updated annually based on global surveillance data. For example, for the 2025-2026 U.S. season, egg-based vaccines include an A/Victoria/4897/2022 (H1N1)pdm09-like virus. The primary indication is prevention of influenza caused by H1N1 viruses.
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