Drug intelligence / Profile preview

H2007

Development stage
Preclinical
Lead developer
Hotgen Biotech
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

H2007 is a therapeutic monoclonal antibody developed by Beijing Hotgen Biotech for the treatment of various cancers. It is designed to modulate the immune system's response to tumors, with a mechanism of action associated with the PD-1/PD-L1 checkpoint pathway. According to pipeline information, H2007 exhibits anti-tumor effects similar to established PD-1/PD-L1 inhibitors and has demonstrated the potential to enhance therapeutic efficacy when used in combination with other checkpoint inhibitors. It is currently being explored as an anti-tumor therapy to improve outcomes in patients with solid tumors.

02

Targets

PDCD1 (Programmed cell death protein 1 receptor)CD274 (Programmed cell death protein 1 ligand 1)

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