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H5N1 adsorbed influenza vaccine is an inactivated vaccine designed to provide active immunization against the H5N1 subtype of the Influenza A virus, commonly known as avian influenza. The term "adsorbed" (frequently translated as "absorbed" in Japanese clinical registries) refers to the use of an aluminum-based adjuvant, such as aluminum hydroxide, to enhance the immune response. This vaccine type has been extensively studied in Japan, with clinical trials sponsored by organizations like the National Hospital Organization Mie National Hospital to evaluate safety, immunogenicity, and the presence of pyrogenic substances. These vaccines are typically monovalent and are intended for use in pandemic preparedness and stockpiling.
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