Drug intelligence / Profile preview

H5N1 adsorbed influenza vaccine

Development stage
Unknown
Lead developer
Biken
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular, Subcutaneous
01

Overview

H5N1 adsorbed influenza vaccine is an inactivated vaccine designed to provide active immunization against the H5N1 subtype of the Influenza A virus, commonly known as avian influenza. The term "adsorbed" (frequently translated as "absorbed" in Japanese clinical registries) refers to the use of an aluminum-based adjuvant, such as aluminum hydroxide, to enhance the immune response. This vaccine type has been extensively studied in Japan, with clinical trials sponsored by organizations like the National Hospital Organization Mie National Hospital to evaluate safety, immunogenicity, and the presence of pyrogenic substances. These vaccines are typically monovalent and are intended for use in pandemic preparedness and stockpiling.

Other names
H5N1 absorbed influenza vaccineH-5N1 absorbed influenza vaccineH 5N1 absorbed influenza vaccineadsorbed H5N1 influenza vaccineinactivated H5N1 whole virion vaccine (adsorbed)
02

Targets

H5 HA (Influenza A hemagglutinin H5)Sialoglycan (Cell-surface sialoglycan)

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