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H5N8 antigen is a viral protein component derived from the H5N8 subtype of highly pathogenic avian influenza (HPAI) virus. It serves as the active ingredient in inactivated vaccines designed to protect poultry, particularly chickens, against H5N8 infection. The antigen works by stimulating the immune system to produce specific antibodies, such as hemagglutination inhibition antibodies, and cellular responses, thereby conferring protection against clinical disease, mortality, and reducing viral shedding upon exposure to the H5N8 virus. It is often used as a benchmark or component in vaccine efficacy studies.
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