Drug intelligence / Profile preview

H5N8 antigen

Development stage
Unknown
Lead developer
CSL Seqirus
Modality
Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

H5N8 antigen is a viral protein component derived from the H5N8 subtype of highly pathogenic avian influenza (HPAI) virus. It serves as the active ingredient in inactivated vaccines designed to protect poultry, particularly chickens, against H5N8 infection. The antigen works by stimulating the immune system to produce specific antibodies, such as hemagglutination inhibition antibodies, and cellular responses, thereby conferring protection against clinical disease, mortality, and reducing viral shedding upon exposure to the H5N8 virus. It is often used as a benchmark or component in vaccine efficacy studies.

02

Targets

H5 HA (Influenza A hemagglutinin H5)

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