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Drug intelligence / Profile preview
HAd5
- Development stage
- Preclinical
- Lead developer
- ImmunityBio
- Modality
- Prophylactic Vaccines → Vaccines & Immunotherapeutics, DNA Vaccines → Plasmid DNA → DNA Therapeutics → Nucleic Acid Therapeutics
- Administration
- Oral, Intramuscular
01
Overview
HAd5 is an adenovirus-based vaccine candidate developed by ImmunityBio, primarily for the prevention and treatment of COVID-19. It was a key component of a joint collaboration between ImmunityBio and its affiliate NantKwest, aiming to combine various immunotherapies for a comprehensive approach against the virus. The vaccine is also being developed for oral delivery through a licensing agreement with iosBio, utilizing their OraPro thermal stabilization platform to create a room-temperature-stable oral capsule, thereby simplifying distribution by eliminating cold-chain requirements.
- Other names
- ImmunityBio COVID-19 vaccinebivalent hAd5 vaccine - ImmunityBiohAd5 T-Cell COVID-19 VaccinehAd-5 T-Cell COVID-19 VaccinehAd 5 T-Cell COVID-19 VaccineSARS-CoV-2 infections vaccine - ImmunityBioSARS-CoV2 infections vaccine - ImmunityBioSARS-CoV 2 infections vaccine - ImmunityBio
02
Targets
N (Nucleocapsid protein)SARS-CoV-2 spike
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