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haemophilus influenzae type b and meningococcal group c conjugate vaccine + measles, mumps and rubella vaccine
- Development stage
- Unknown
- Lead developer
- GSK
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular, Subcutaneous
01
Overview
The Hib-MenC-TT conjugate vaccine + MMR vaccine refers to the concomitant administration of a combined Haemophilus influenzae type b and Neisseria meningitidis serogroup C tetanus toxoid conjugate vaccine (marketed as Menitorix) with a measles, mumps, and rubella (MMR) vaccine (marketed as Priorix). Developed by GSK, this combination is typically administered as a booster dose in toddlers aged 12-15 months to provide simultaneous protection against five major pediatric infectious diseases. The Hib-MenC-TT component utilizes purified capsular polysaccharides from Hib and MenC bacteria, each conjugated to a tetanus toxoid carrier protein to enhance immunogenicity and induce T-cell dependent memory. The MMR component consists of live attenuated measles, mumps, and rubella viruses that replicate to stimulate long-lasting humoral and cellular immunity. Clinical trials have demonstrated that these vaccines can be safely co-administered without significant interference in immune responses or increased safety concerns compared to separate administration.
- Brand names
- MenitorixPriorix
- Other names
- Hib-MenC-TT + MMR vaccineHib-MenC-TT conjugate vaccine + MMR vaccineMenitorix + Priorix
02
Targets
Mumps virus antigenNeisseria meningitidis group C capsular polysaccharideMV (Measles virus)TT (Tetanus toxoid)
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