Haflone Plus

Haflone Plus is a brand name used by Hanbet Pharmaceuticals for two distinct antimalarial drug products marketed in Nigeria. The most prominent formulation, particularly in clinical and regulatory contexts involving parenteral administration, is **Haflone Plus Injection**, which contains **artemether** (80 mg/ml). Artemether is a lipid-soluble artemisinin derivative that acts as a rapidly acting blood schizonticide by generating reactive free radicals upon interaction with heme within the malaria parasite's food vacuole. These radicals alkylate and damage essential parasitic proteins and membranes, leading to parasite death. The second product is **Haflone Plus Tablet**, which contains **halofantrine hydrochloride** (500 mg), a phenanthrene methanol antimalarial that interferes with the degradation of hemoglobin. Both products are approved for the treatment of malaria, with the injection specifically indicated for severe or chloroquine-resistant cases caused by *Plasmodium falciparum*.

Brand names

Haflone Plus

Other names

artemetherhalofantrine