Drug intelligence / Profile preview

hainosankyuto

Development stage
Unknown
Lead developer
Tsumura
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Hainosankyuto is a traditional Japanese Kampo medicine (a standardized herbal formulation) used for the treatment of suppurative inflammatory conditions, such as skin infections (boils, carbuncles) and dental diseases (periodontal abscesses, periodontitis). It is a fixed combination of six crude drugs: Platycodon Root, Peony Root, Jujube, Immature Orange, Ginger, and Licorice. The formulation is designed to reduce inflammation, promote the drainage of pus, and facilitate wound healing. In Japan, it is regulated as a pharmaceutical product and is often used as an adjunct to antibiotic therapy to accelerate the resolution of acute inflammatory lesions. Clinical trials have specifically evaluated its efficacy in combination with amoxicillin for managing acute periodontal inflammation.

Brand names
Tsumura HainosankyutoKracie HainosankyutoKotaro Hainosankyuto
Other names
HainosankyutoHai-No-San-Kyu-To排膿散及湯
02

Targets

TNFA (Tumor necrosis factor alpha (soluble))IL-6 (Interleukin 6)

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