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haishosan-kyokuto
- Development stage
- Unknown
- Lead developer
- Kyokuto Securities
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Haishosan-kyokuto is a Japanese Kampo (herbal) medicine manufactured by Kyokuto Pharmaceutical Industrial. It is based on the traditional Haishosan formula, which is indicated for the treatment of purulent skin diseases and inflammatory conditions characterized by suppuration, such as abscesses and boils. The formulation typically consists of three botanical ingredients: Platycodon root (Kikyō), Paeonia root (Shaku-yaku), and Immature Orange (Kijitsu). In the context of dental medicine, it is being investigated as an adjunctive treatment to amoxicillin for managing acute exacerbations of periodontitis and periodontal abscesses, aiming to improve wound healing and reduce local inflammation by promoting the drainage of pus and modulating inflammatory signaling pathways.
- Brand names
- Haishosan-kyokuto
- Other names
- HaishosanHainosanHainosan-kyokuto
02
Targets
NF-κBTNFA (Tumor necrosis factor alpha (soluble))IL-6 (Interleukin 6)
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